The Ovovac study for the diagnosis of pancreatic cancer from the blood will take up to half a year

The Ovovac study for the diagnosis of pancreatic cancer from the blood will take up to half a year
The Ovovac study for the diagnosis of pancreatic cancer from the blood will take up to half a year

Until then, it will be necessary to prepare the protocol of the study, which was approved by the State Government for Life Control and the Ethics Commission, and to agree on the institutions that will take part in it. Comprehensive oncology centers from all over the country should be involved.

Marek Svoboda, the editor of Masaryk’s oncological status, told the newspaper today.

Our goal is to involve all oncology centers, at this moment we only have six of them. We have to fine-tune the storage sample, which requires a specific time, frozen, and we want to equip other centers so that they can all be involved and patients across the country can be collected for the study, said Svoboda.

Pancreatic cancer is the most common type of cancer. It is difficult to recognize it, as there is currently no approved non-invasive method of detecting it or a preventive screening program in the world. The disease succumbs and 87 percent of the patients. In 2022, there were no more than 2,400 new cases diagnosed in the Czech Republic.

This method should go a long way. She should find out which patient is at risk, who should undergo an operation or a diagnostic procedure with tissue sampling. These are all things that this method will stick to in the future and possibly move to other populations as well, said Svoboda.

The bin method of pancreatic cancer diagnosis could be used for screening people with risk factors. Among them there are, for example, diseases, some types of diabetes, chronic pancreatitis or genetic diseases. At the moment, there is no suitable method for screening, other survey methods have detected the disease in late stages.

If a patient is found to have a pancreatic cyst, it is because he had a huge cyst. It’s not worth lying in, he broke his arm, he went for a CT scan and they found it there. With this method, we are able to capture a tumor that cannot be seen with imaging methods, said Minister of Health Vlastimil Vlek (TOP 09).

In Holapk’s dark methods, plasma or serum is separated from the blood after the sample is taken, and lipids are then separated in the laboratory. With the help of a chromatographic column, it is stratified according to individual molecules, then in a mass spectrometer it is separated according to weight. Individual molecules are identified, their representation is determined and the spectrum is compared with the profiles of sick and healthy people who are statistically significant. The accuracy of pancreatic cancer diagnosis is about 90 percent.

In April, the University of Pardubice joined the company Lipidica, which was founded by the esk holding FONS JK Group. The company wants to put into practice the method for early detection of pancreatic cancer, which it has patented. The capacity of its laboratory reaches 20,000 samples per year and could be used for large-scale screening. Lipidica is the sponsor of the study and will provide the laboratory for the study.

The article is in Czech

Tags: Ovovac study diagnosis pancreatic cancer blood year


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